Peter Taylor's faltering side were held by a resurgent Morecambe, who extended their own unbeaten run to eight games, their best ever since winning promotion to the Football League, with another solid display.
The Chairboys once again were grateful to the ever reliable defensive pairing of Leon Johnson and Dave McCracken, who held the back line superbly to keep out a spirited challenge from Sammy McIlroy's in-form side and in doing so kept their 17th clean sheet of the season.
Despite being disappointed with his side's drop to third in the table after Rochdale's victory over Grimsby boss Peter Taylor says his side won't be panicking yet with 14 games of a long season to go.
In a game of few chances the home side enjoyed the majority of the possession, but came up against a well drilled Wycombe defence who showed once again why they are the league's tightest.
The Shrimps came the closest to scoring in the first half when midfielder Stewart Drummond tried a delicate chip on the half hour that beat Jamie Young, but landed on the top of the netting.
In the second half Michael Twiss headed a Garry Hunter corner just over at the near post, before Hunter tried to match his superb midweek strike with another long-range effort that just cleared the crossbar.
Wycombe's best effort came on 38 minutes when Matt Harrold tried to convert a fine, low cross from Matt Phillips, but saw the ball fall into Barry Roche's hands.
They did have the ball in the back of the net just after the hour but Lewwis Spence's effort was ruled out for a narrow offside after a neat interchange with Stuart Beavon.
With both defences very much on top Morecambe striker Diarmuid O'Carroll tried his luck from the edge of the area with a stinging shot that forced Young into a neat save and then headed straight at Young from an Adam Yates cross in the final stages.